Chemistry

Chemistry

Identification of Connexin 50 (GJA8) Gene Mutations in Microphthalmia, Anophthalmia & Coloboma

Connexins are transmembrane proteins that form gap junctions and hemichannels and allow ions and small molecules to pass from one cell to another or from the cell into its environment, respectively. Since gap junctions are the main means of communication between adjacent cells, they are vital to the function of multicellular organisms.

Nobel Prize in Chemistry Awarded to Chemists Who Developed Super-resolved Fluorescent Microscopy

On October 8th, the Nobel Prize in Chemistry was jointly awarded to three chemists who developed super-resolved fluorescent microscopy. Dr. Eric Betzig of the Janelia Research Campus at Howard Hughes Medical Institute in Virginia, Dr. Stefan W. Hell of the Max Planck Institute for Biophysical Chemistry and German Cancer Research Center, and Dr. William E. Moerner of Stanford University were jointly awarded the prize for their groundbreaking work in the field of microscopy done in the early 2000s.

Decoy Protein Inhibits Metastatic Cancer Progression

Researchers at Stanford have recently synthesized a "decoy receptor" that binds and inactivates a protein known to cause cancer. Axl receptor tyrosine kinase has been associated with the growth of metastatic cancer, which is cancer that has spread throughout the body and is not confined to one area. Axl promotes metastatic cancer by binding Gas-6 ligand; two Gas-6 ligands join two Axl receptors, which signal cancer cells to migrate to other parts of the body.[1] The discovery of the mechanism of Axl has allowed researchers to target both Axl and Gas-6 in therapeutic studies.

News

UD in the Community: Gospel of Life Dwellings Affirm Lives

Although she can no longer see, Tia does her best, like the mother she still is, to ensure the comfort of those around her from her perch on the edge of her bed. She is one of three elderly residents of St. Adelaide in Grand Prairie, one of Gospel of Life Dwellings' two locations. First conceived by Joe Flaherty, M.D., BA '86, a geriatrician, the idea for these homes was embraced and implemented -- and is continuously sustained -- by numerous UD alumni.

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New Crusader Baseball Clubhouse Completed

Positioned off Crusader Drive, behind the batting cages and the centerfield wall of the baseball field, the university's newly constructed baseball clubhouse opened the first week in May, the last week of the season for the UD baseball team. This milestone marked the end of a years-long endeavor supported by the university's Baseball Booster Club to upgrade the team's existing locker room and practice facilities.

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