Chemistry

Chemistry

Identification of Connexin 50 (GJA8) Gene Mutations in Microphthalmia, Anophthalmia & Coloboma

Connexins are transmembrane proteins that form gap junctions and hemichannels and allow ions and small molecules to pass from one cell to another or from the cell into its environment, respectively. Since gap junctions are the main means of communication between adjacent cells, they are vital to the function of multicellular organisms.

Nobel Prize in Chemistry Awarded to Chemists Who Developed Super-resolved Fluorescent Microscopy

On October 8th, the Nobel Prize in Chemistry was jointly awarded to three chemists who developed super-resolved fluorescent microscopy. Dr. Eric Betzig of the Janelia Research Campus at Howard Hughes Medical Institute in Virginia, Dr. Stefan W. Hell of the Max Planck Institute for Biophysical Chemistry and German Cancer Research Center, and Dr. William E. Moerner of Stanford University were jointly awarded the prize for their groundbreaking work in the field of microscopy done in the early 2000s.

Decoy Protein Inhibits Metastatic Cancer Progression

Researchers at Stanford have recently synthesized a "decoy receptor" that binds and inactivates a protein known to cause cancer. Axl receptor tyrosine kinase has been associated with the growth of metastatic cancer, which is cancer that has spread throughout the body and is not confined to one area. Axl promotes metastatic cancer by binding Gas-6 ligand; two Gas-6 ligands join two Axl receptors, which signal cancer cells to migrate to other parts of the body.[1] The discovery of the mechanism of Axl has allowed researchers to target both Axl and Gas-6 in therapeutic studies.

News

Parents Support University in Late Daughter's Memory

Mike Kiegerl's youngest daughter, Christine, would have graduated from UD in the Class of 1994, but just before her graduation, she was struck by an impaired truck driver and died instantly. Kiegerl and his wife, Peggy, established the Christine S. Kiegerl Memorial Scholarship in their girl's memory in 1997.

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UD in Service: Ph.D. Students Share 'Confessions' in South Irving

UD students not only read St. Augustine's "Confessions" in Rome, traveling to Ostia to marvel at the place in which, according to Book IX, St. Augustine and his mother, St. Monica, had a joint mystical vision of God — they also travel 4.4 miles from the Irving campus to read the text with residents of South Irving.

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