Chemistry

Chemistry

Identification of Connexin 50 (GJA8) Gene Mutations in Microphthalmia, Anophthalmia & Coloboma

Connexins are transmembrane proteins that form gap junctions and hemichannels and allow ions and small molecules to pass from one cell to another or from the cell into its environment, respectively. Since gap junctions are the main means of communication between adjacent cells, they are vital to the function of multicellular organisms.

Nobel Prize in Chemistry Awarded to Chemists Who Developed Super-resolved Fluorescent Microscopy

On October 8th, the Nobel Prize in Chemistry was jointly awarded to three chemists who developed super-resolved fluorescent microscopy. Dr. Eric Betzig of the Janelia Research Campus at Howard Hughes Medical Institute in Virginia, Dr. Stefan W. Hell of the Max Planck Institute for Biophysical Chemistry and German Cancer Research Center, and Dr. William E. Moerner of Stanford University were jointly awarded the prize for their groundbreaking work in the field of microscopy done in the early 2000s.

Decoy Protein Inhibits Metastatic Cancer Progression

Researchers at Stanford have recently synthesized a "decoy receptor" that binds and inactivates a protein known to cause cancer. Axl receptor tyrosine kinase has been associated with the growth of metastatic cancer, which is cancer that has spread throughout the body and is not confined to one area. Axl promotes metastatic cancer by binding Gas-6 ligand; two Gas-6 ligands join two Axl receptors, which signal cancer cells to migrate to other parts of the body.[1] The discovery of the mechanism of Axl has allowed researchers to target both Axl and Gas-6 in therapeutic studies.

News

Art Alumna's Vintage Dress Design to Debut on Red Carpet

Dallas-area native and Door Number 9 designer Elisa Choffel Low, BA '03, will have her latest dress design showcased on the red carpet at the Emmy Awards in Los Angeles on Sunday, Sept. 22. The silver open-back vintage-style gown includes a striking chainmail jewelry inset created in collaboration with Toronto jewelry designer Kyra Matsui.

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University Welcomes Leading Catholic Intellectual to Campus

On Friday, Sept. 13, the university community welcomed George Weigel, distinguished senior fellow of the Ethics and Public Policy Center and the father of two UD alumnae. Celebrated for his two-volume biography of St. John Paul II and many other intellectual contributions, Weigel presented an exploration of the current Catholic situation in light of a new interpretation of the past 250 years of the church's interaction with social, cultural, economic and political modernity.

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Recent DBA Alumnus Begins Tenure-Track Position at UNI

Gabe Dickey, DBA '19, recently successfully defended his dissertation, titled "Exploring the Human Side of Audit Quality: Team Engagement and Partner Leadership Behaviors," for UD's Doctor of Business Administration. Dickey has spent his career in the accounting profession, the vast majority as a certified public accountant working in auditing. He began UD's DBA program three years ago, drawn in by his interest in broader business issues and the program's practitioner-oriented focus.

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