Visual circuit neurons in Drosophila.
As geneticists, the Stenesen Lab is interested in the encoding, processing and utilization
of biological information. Beyond the molecular, our investigations extend into the
nervous system with the goal of understanding how sensory information is transmitted
to influence a behavioral response. To discover the basis of such events we employ
genetic and cell biological approaches within the Drosophila model system.
Nociception is the sensory response to harmful stimuli. This process is commonly associated with
the sense of pain, and is how body tissues are protected from damage. We utilize the
nociceptive escape response of Drosophlia to monitor the impact of genetic and cellular
alterations on circuit function.