Abdallah Elnwasany, M.D.
Affiliate Assistant Professor of Biology
Phone: (972) 721-5170
Email: aelnwasany@udallas.edu
Office: Haggerty Science Center #028
Office Hours: https://calendar.app.google/XgfjHnkbvJ81NvKv6
Originally from Egypt, Dr. Elnwasany graduated from the University of Alexandria Medical School. He completed his postdoctoral fellowship in the Division of Cardiology, Department of Internal Medicine, at UT Southwestern Medical Center in Dallas, Texas, and joined the UT Southwestern faculty in 2023. Dr. Elnwasany began teaching at the University of Dallas as an adjunct faculty member in 2022 and was appointed Affiliate Assistant Professor of Anatomy and Physiology in 2024.
Dr. Elnwasany's research focuses on heart metabolism, with an emphasis on understanding how insulin regulates the utilization of glucose and fat in the heart. His work investigates the mechanisms through which dietary changes impact cardiac and mitochondrial metabolism and explores how diet-induced metabolic alterations affect insulin signaling and overall cardiovascular health. His investigations have resulted in significant contributions to the field through his publications.
M.D., Alexandria University, Faculty of Medicine, Alexandria, Egypt
Postdoctoral Fellowship
Department of Internal Medicine, Cardiology Division, UT Southwestern Medical Center,
Dallas, Texas
Postdoctoral Certificate in Research, UT Southwestern Medical Center, Southwestern Graduate School of Biomedical science
Postdoctoral Certificate in Advanced Research, UT Southwestern Medical Center, Southwestern Graduate School of Biomedical science
BIO 3123 – Anatomy Lab
BIO 3331 – Physiology
BIO 3131 – Physiology lab
BIO 3141 – Medical Terminology
BIO 1312 – Gen Biology 2
BIO 1111 – Gen Biology 1 Lab
BIO 1112 – Gen Biology 2 Lab
| Row | Column |
|---|---|
| 2004 – 2006 | Alexandria University Medical School Distinction Award, Egypt |
| 2017 – 2019 | Department of Health and Human Services Public Health Service Ruth L. Kirschstein National Research Service Award |
| 2022 – 2023 | The Hamon Center for Regenerative Science and Medicine UT Southwestern Medical Center Trainee Fellowship |
1. Reciprocal Regulation of Cardiac β-Oxidation and Pyruvate Dehydrogenase by Insulin. Elnwasany A., Ewida H.A., Menendez-Montes I., Mizerska M., Fu X., Kim C-W., Horton J.D., Burgess S.C., Rothermel B.A., Szweda P.A., and Szweda L.I. (2024) J. Biol. Chem., (2024).107412
2. Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization. Hande C Piristine, Herman I May, Nan Jiang, Daniel Daou, Francisco Olivares-Silva, Elnwasany A., Pamela Szweda, Luke Szweda, Caroline Kinter, Michael Kinter, Gaurav Sharma, Xiaodong Wen, Craig R Malloy, Michael E Jessen, Thomas G Gillette, Joseph A Hill. bioRxiv, (2024) .09. 17.613531
3. Hypoxia-Induced Stabilization of HIF2A Promotes Cardiomyocyte Proliferation by Attenuating DNA Damage. Shah S.A., Nguyen N.U.N, Menendez-Montes I., Hsu C.-C., Elhelaly W., Lam N.T., Li S., Elnwasany A., Nakada Y., Thet S., Foo R.S.Y., and Sadek H.A. (2024) Journal of Cardiovascular Aging, 4, 11
4. Transcription Factor NFYa Controls Cardiomyocyte Metabolism and Proliferation During Mouse Fetal Heart Development. Cui M., Bezprozvannaya S., Hao T., Elnwasany A., Szweda L.I., Liu N., Bassel-Duby R., and Olson E.N. (2023) Dev. Cell 58, 2867-2880
5. Inhibition of Pyruvate Dehydrogenase in the Heart as an Initiating Event in the Development of Diabetic Cardiomyopathy. Elnwasany A., Ewida H.A., Szweda P.A., and Szweda L.I. (2023) Antioxidants 12, 756
6. PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. Li Q., Li C., Elnwasany A., Sharma G., An Y.A., Zhang, G., Elhelaly W.M., Lin J., Gong Y., Chen G., Wang M.H., Zhao S., Dai C., Smart C.D., Liu J., Luo X., Deng Y., Tan L., Lv S.-J., Davidson S.M., Locasale J.W., Lorenzi P.L., Malloy C.R., Gillette T.G., Vander Heiden M.G., Scherer P.E., Szweda L.I., Fu G., Wang Z.V. (2021) Circulation, 144, 712-727
7. NAD+ Repletion Reverses Heart Failure with Preserved Ejection Fraction. Tong, D., Schiattarella G.G., Jiang N., Altamirano F., Szweda P.A., Elnwasany A., Lee D.I., Yoo H., Kass D.A., Szweda L.I., Lavendero S., Verdin E., Gillette T.G., Hill J.A. (2021) Circ. Res., 128, 1629-1641
8. Mitochondrial Metabolism is a Key Regulator of the Fibro-Inflammatory and Adipogenic Stromal Subpopulations in White Adipose Tissue. Joffin N., Paschoal V.A., Gliniak C.M., Crewe C., Elnwasany A., Szweda L.I., Zhang Q., Hepler C., Kusiminski C.M., Gordillo R., Oh D.Y., Gupta R.K., Scherer P.E. (2021) Cell Stem Cell., 28, 708-717
9. Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression. Nature Metabolism. Cardoso A.C., Lam N.T., Savla J.J., Nakada Y., Pereira A.H.M., Elnwasany A., Menendez-Montes I., Ensley E.L., Petric U.B., Sharma G., Sherry A.D., Malloy C.R., Khemtong C., Kinter M.T., Wilson Tan L.W.T., Anene-Nzelu C.G., Roger Foo S.Y., Nguyen N.U.N, Li S., Ahmed M.S., Elhelaly W.M., Abdisalaam S., Asaithamby A., Xing C., Kanchwala M., Vale G., Eckert K.M., Mitsche M.A., McDonald J.G., Hill J.A., Huang L., Shaul P.W., Szweda L.I., Sadek H.A. Nature Metabolism. (2020) 2, 167-178
10. C-Kit Cells Do Not Significantly Contribute to Cardiomyogenesis During Neonatal Heart Regeneration. Elhelaly W.M., Cardoso A.C., Pereira A.H.M., Elnwasany A., Ebrahimi S., Nakada Y., and Sadek H.A. (2019) Circulation 139 (4), 559-561
11. Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice. Schafer, C., Young, Z.T., Makarewich, C.A., Elnwasany, A., Kinter, C., Kinter, M., and Szweda, L.I. (2018) J. Biol. Chem., 293, 6915-6924
1. Advances in Heart Metabolism: Current Research Insights and Future Directions. Oral Presentation, University of Dallas, Irving, Texas, June 2024
2. Metabolic Flexibility and its Impact on Heart Function. Oral Presentation, Cardiovascular Biology WIPs meeting, Dallas, Texas, November 2023
3. Regulation of Glucose Relative to Fatty Acid Oxidation in the Heart. Oral Presentation, Cardiovascular Biology WIPs Meeting, Dallas, Texas, November 2022
4. CoASH Plays a Key Role in Insulin-Dependent Activation of Pyruvate Dehydrogenase in the Heart, Leducq Redox Network video meeting, November 2021
5. Determinants of Glucose Verses Fat Utilization in the Heart. Oral Presentation, Leducq Redox Network meeting, Philadelphia, Pennsylvania, November 2019
6. Diet-Induced Determinants in Cardiac Metabolism. Oral Presentation, Leducq Redox Network meeting, New York City, New York, November 2018